The conference will cover the following topics:
1. The causes and consequences of deficiencies in the metabolism of B vitamins and homocysteine
2. Genetic polymorphisms affecting one-carbon metabolism
3. Epigenetic mechanisms in hyperhomocysteinemia and B vitamin deficiencies
4. Effects of microbiome on homocysteine/one-carbon metabolism; the role of dysbiosis in human disease
5. Interactions between homocysteine, B vitamins, and reproduction
6. Dysregulation of homocysteine/one-carbon metabolism and the development of neurological diseases
7. Functions of choline in one-carbon metabolism in health and disease

Preliminary program:
Session 1: Genetics and epigenetics of hyperhomocysteinemia
Session 2: Methionine, one-carbon metabolism, and life span
Session 3: Microbiome and one-carbon metabolism in health and disease
Session 4: Protein modification by homocysteine in health and disease
Session 5:B-vitamins, Hcy, and protein N-homocysteinylation (neural tube defects; male infertility)
Session 6: Hcy and CVD (brain, heart, kidney)
Session 7: Hcy and neurodegeneration (brain, eye)
Session 8: Hcy, one-carbon metabolism, and cancer

www.homocysteine2021.org


Hieronim Jakubowski
Rutgers University, Newark, NJ, USA

Joanna Perła-Kaján

Uniwersytet Przyrodniczy w Poznaniu
Katedra Biochemii i Biotechnologii

Maksymalny koszt udziału: 1300 zł
Strona www: http://www.homocysteine2021.org

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